Description: Biology of Extracellular Molecular Chaperones, Hardcover by Novartis Foundation (EDT), ISBN 0470723335, ISBN-13 9780470723333, Brand New, Free shipping in the US This volume presents the proceedings of an eponymously-titled symposium held at the Novartis Foundation in London, UK, in June 2007 and dealing with the mechanisms and effects of extracellular molecular chaperones (proteins that assist non-covalent folding and unfolding of other macromolecular structures but do not occur in these structures when the structures are performing their normal biological functions). Topics addressed in the 14 included presentations are the history of the understanding of cell stress; systems biology of molecular chaperone networks; unusual cellular disposition of the mitochondrial chaperones Hsp60, Hsp70, and Hsp10; cell surface molecular chaperones as endogenous modulators of innate immune response; cell stress proteins in extracellular fluids; Hsp60 and the immune system; novel immunotherapies from cell stress proteins; cell stress proteins as modulators of bacteria-host interactions; chaperonin 60 and microphage activation; extracellular functions of thioredoxin; Hsp27 as an anti-inflammatory and immunomodulatory stress protein acting to dampen immune function; and binding immunoglobulin protein as a potential new therapy for the treatment of rheumatoid arthritis. Annotation ©2008 Book News, Inc., Portland, OR ()
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Number of Pages: 248 Pages
Publication Name: Biology of Extracellular Molecular Chaperones
Language: English
Publisher: Wiley & Sons, Incorporated, John
Publication Year: 2008
Item Height: 0.7 in
Subject: Life Sciences / Cell Biology
Type: Textbook
Item Weight: 19 Oz
Subject Area: Science
Item Length: 9.1 in
Author: Jamie A. Goode
Series: Novartis Foundation Symposia Ser.
Item Width: 6.3 in
Format: Hardcover
