Genomic Imprinting Causes and Consequences Ohlsson Hall Ritzen Paperback

Description: Genomic Imprinting Causes and Consequences This significant 1995 publication deals with genomic or parental imprinting. R. Ohlsson (Edited by), K. Hall (Edited by), M. Ritzen (Edited by) 9780521179997, Cambridge University Press Paperback / softback, published 17 February 2011 396 pages 24.4 x 17.7 x 2.1 cm, 0.63 kg Review of the hardback: '... a good introduction to the subject'. Carmen Sapienza Originally published in 1995, this significant publication on genomic or parental imprinting was prepared by an outstanding team of international authorities. Genomic imprinting results in the preferential expression of one allele, depending on the parent of origin. It is associated with several disease syndromes in humans. Interest in this area has expanded rapidly from the time when it was first recognised that some aspects of inheritance were not adequately explained by the Mendelian laws. The chapters cover a wealth of material to help explain not only the mechanisms of genomic imprinting but also its biological and medical consequences. This interdisciplinary volume encompasses clinical genetics, pathology, developmental biology, evolution and genetics. It will be of interest to all scientists and clinicians working in this area. Contributors Part I. Genomic Imprinting in Mammals: 1. The role of imprinting in early mammalian development A. Gilligan, and D. Solter 2. The evolution of parental imprinting: a review of hypotheses D. Haig and R. Trivers 3. Genetic variations in parental imprinting on mouse chromosome 17 J. Forejt, S. Gregorovà, M. Landíková, J. Capková and L. M. Silver Part II. Chromatin Structure and DNA Modifications: 4. Epigenetic inheritance: the chromatin connection A. P. Wolffe 5. Chromobox genes and the molecular mechanisms of cellular determination P. B. Singh and T. C. James 6. The biochemical basis of allele-specific gene expression in genomic imprinting and X inactivation T. H. Bestor 7. DNA methylation and mammalian development R. Jaenisch, C. Beard and E. Li Part III. Mechanisms of Imprinting: 8. X chromosome inactivation and imprinting M. F. Lyon 9. Imprinting of H19 and Xist in uniparental embryos M. A. Surani, A. C. Ferguson-Smith, H. Sasaki and S. C. Barton 10. Imprinted genes, allelic methylation, and imprinted modifiers of methylation W. Reik, R. Feil, N. D. Allen, T. F. Moore and J. Walter 11. Genomic imprinting of the H19 and Igf2 genes in the mouse S. M. Tilgham, M. S. Bartolomei, A. L. Webber, M. E. Brunkow, J. Saam, P. A. Leighton and K. Pfeifer 12. Plasticity of imprinting R. Ohlsson, T. Ekström, G. Franklin, S. Pfeifer-Ohlsson, H. Cui, S. Miller, R. Fisher and C. Walsh 13. Regional regulation of allele-specific gene expression I. Simon and H. Cedar Part IV. Genomic Imprinting in Embryonal Tumors and Overgrowth Disorders: 14. Genomic imprinting in embryonal tumors and overgrowth disorders A. E. Reeve 15. Tracking imprinting: the Beckwith-Wiedemann syndrome M. Mannens 16. Genomic imprinting in Beckwith-Wiedemann syndrome R. Weksberg and J. Squire 17. Mitotic crossing over and the disruption of genomic imprinting G. B. Côté 18. Evaluating H19 as an imprinted tumor suppressor gene B. Tycko 19. A domain of abnormal imprinting in human cancer A. P. Feinberg Part V. Genomic Imprinting and the Prader-Willi Syndrome: 20. Parent-of-origin-specific DNA methylation and imprinting mutations on human chromosome 15 B. Horsthemke, B. Dittrich and K. Buiting 21. The SNRPN gene and Prader-Willi syndrome U. Francke, J. A. Kerns and J. Giacalone Part VI. Imprinting: A Search for New Genes and Unifying Principles: 22. Use of chromosome rearrangements for investigations into imprinting in the mouse B. M. Cattanach, J. Barr and J. Jones 23. A new imprinted gene, U2af-related sequence, isolated by a methylation-sensitive genome scanning method T. Mukai, I. Hatada, T. Yamaoka, K. Kitagawa, X.-D. Wang, T. Sugama, J. Masuda and J. Ogata 24. The mouse Igf2/MPR gene: a model for all gametic imprinted genes? D. P. Barlow Index. Subject Areas: Developmental biology [PSC], Genetics [non-medical PSAK]

Price: 36.99 GBP

Location: AL7 1AD

End Time: 2024-12-17T02:00:42.000Z

Shipping Cost: 126.12 GBP