Description: X-ray Diffraction Imaging of Biological Cells, Hardcover by Nakasako, Masayoshi, ISBN 4431566163, ISBN-13 9784431566168, Like New Used, Free shipping in the US
In this book, the author describes the development of the experimental diffraction setup and structural analysis of non-crystalline particles from material science and biology. Recent advances in X-ray free electron laser (XFEL)-coherent X-ray diffraction imaging (CXDI) experiments allow for the structural analysis of non-crystalline particles to a resolution of 7 nm, and to a resolution of 20 nm for biological materials. Now XFEL-CXDI marks the dawn of a new era in structural analys of non-crystalline particles with dimensions larger than 100 nm, which was quite impossible in the 20th century.
To conduct CXDI experiments in both synchrotron and XFEL facilities, the author has developed apparatuses, named KOTOBUKI-1 and TAKASAGO-6 for cryogenic diffraction experiments on frozen-hydrated non-crystalline particles at around 66 K. At the synchrotron facility, cryogenic diffraction experiments dramatically reduce radiation damage of specimen particles and allow tomography CXDI experiments. In addition, in XFEL experiments, non-crystalline particles scattered on thin support membranes and flash-cooled can be used to efficiently increase the rate of XFEL pulses. The rate, which depends on the number density of scattered particles and the size of X-ray beams, is currently 20-90%, probably the world record in XFEL-CXDI experiments. The experiment setups and results are introduced in this book. The author has also developed software suitable for efficiently processing of diffraction patterns and retrieving electron density maps of specimen particles based on the diffraction theory used in CXDI.
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Book Title: X-Ray Diffraction Imaging of Biological Cells
Number of Pages: Xx, 228 Pages
Language: English
Publisher: Springer Japan
Topic: Lasers & Photonics, Materials Science / General, Physics / Optics & Light, Life Sciences / Cell Biology, Radiation, Microscopes & Microscopy
Publication Year: 2018
Illustrator: Yes
Genre: Technology & Engineering, Science
Item Weight: 19.1 Oz
Item Length: 9.3 in
Author: Masayoshi Nakasako
Book Series: Springer Series in Optical Sciences Ser.
Item Width: 6.1 in
Format: Hardcover
